Product Description
Catalog Number | PKSH033771 |
Product Name | Recombinant Human Alpha-Synuclein/SNCA Protein (Active) |
Background | Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1; Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition; SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).. |
Synonym | Alpha-Synuclein; Non-A Beta Component of AD Amyloid; Non-A4 Component of Amyloid Precursor; NACP; SNCA; NACP; PARK1 |
Species | Human |
Expressed Host | E.coli. |
Fusion tag | |
Sequence | Met1-Ala140 |
Accession | P37840 |
Purity | > 95% as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per ?g as determined by the LAL method. |
Stability and Storage | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months. |
Formulation | Lyophilized from a 0.2 ?m filtered solution of PBS;PH7.4.. |
Document |
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Elabscience
Questions about this product? Email us at orders@iwai-chem.com or give us a call: (650) 486-1541 |