Product Description
| Catalog Number | E-AB-22009 |
| Product Name | CD45 Monoclonal Antibody |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Applications | WB,IHC-p |
| Reactivity | Human |
| Host | Mouse |
| Clone | Clone:3H3 |
| Swissprot | P08575 |
| Dilution | WB 1:500-1:2000, IHC 1:50-300 |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Document |
Manufacturer by Elabscience
This product is for Research Purposes Only