Product Description
| Product Name | Cat# | Clone# | Unit Size | Isotype | Applications | Reactivity |
| Anti-Human RUNX1 | BMR00311 | RUNXA3B6 | 100ug/ml (1ml) | IgG1 | DB,WB | Hu |
* Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Two transcript variants encoding different isoforms have been found for this gene. [NCBI Entrez Gene Summary]
*Quality of Control
Data Sheet BMR00311 (PDF File)
Western blot protocol (PDF File)
| Antibody Concentration | 100 ug/ml (1.0 ml) |
| Host Species | Mouse |
| Preparation | This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Sterility | Filtered through a 0.22 um membrane. |
| Alternate Names | AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1 |
| Accession No. | NM_001754 |
Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Bio Matrix Research, Inc.
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