Product Description
| Product Name | Cat# | Clone# | Unit Size | Isotype | Applications | Reactivity |
| Anti-Human RHOB | BMR00474 | 2916C2a | 100ug/ml (1ml) | IgG1 | DB,WB | Hu |
* Background
Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. [UniProtKB?Function]
*Quality of Control
Data Sheet BMR00474 (PDF File)
Western blot protocol (PDF File)
| Antibody Concentration | 100 ug/ml (1.0 ml) |
| Host Species | Mouse |
| Preparation | This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Sterility | Filtered through a 0.22 um membrane. |
| Alternate Names | ARH6, ARHB, RHOH6, MST081, MSTP081 |
| Accession No. | NM_004040 |
Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Manufactured by : Bio Matrix Research, Inc.
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